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Jennifer Aniston and Drew Barrymore joined forces to support their frequent onscreen leading man Adam Sandler as he was honored with the 24th Annual Mark Twain Prize for American Humor at The Kennedy Center in Washington, DC on Sunday.

The 56-year-old Frat Packer – who sported a burly beard – cleaned up well in a black baggy suit and necktie as he accepted the distinguished honor, and the star-studded ceremony airs next Sunday on CNN.

And the San Fernando Valley natives weren’t alone as Adam’s wife Jacqueline Titone, whom he kissed on the cheek onstage during the festivities.

Sandler and the 48-year-old Daddy Daughter Trip actress will impressively celebrate their 20th wedding anniversary on June 22.

The Brooklyn-born comedian and Jackie are proud parents of 16-year-old daughter Sadie Madison and 14-year-old daughter Sunny Madeline.

Standing ovation! Jennifer Aniston (L) and Drew Barrymore (R) joined forces to support their frequent onscreen leading man Adam Sandler as he was honored with the 24th Annual Mark Twain Prize for American Humor at The Kennedy Center in Washington, DC on Sunday

Standing ovation! Jennifer Aniston (L) and Drew Barrymore (R) joined forces to support their frequent onscreen leading man Adam Sandler as he was honored with the 24th Annual Mark Twain Prize for American Humor at The Kennedy Center in Washington, DC on Sunday

Suited and booted: The 56-year-old Frat Packer - who sported a burly beard - cleaned up well in a black baggy suit and necktie as he accepted the distinguished honor, and the star-studded ceremony airs next Sunday on CNN

Suited and booted: The 56-year-old Frat Packer – who sported a burly beard – cleaned up well in a black baggy suit and necktie as he accepted the distinguished honor, and the star-studded ceremony airs next Sunday on CNN

‘What a nice night! I never expected anything like this. Nobody did,’ Adam said of the honor earlier to uproarious laughter.

‘But it’s not something we thought of in our life. But the fact that it happened and I get to say this for the rest of my life and I do have a lot of people on the street now coming up to me. They’re going, “Yeah, Mark Twain, Sandman.” I’m like, “Okay!” I didn’t know that was going to happen so it’s cool as hell.’

Meanwhile, 54-year-old Jen and 48-year-old Drew – both glammed up in not-so-basic black attire – have co-starred with Adam in three films, respectively.

Aniston and Sandler collaborated on Dennis Dugan’s 2011 rom-com Just Go with It, Kyle Newacheck’s 2020 who-done-it Murder Mystery, and Jeremy Garelick’s sequel Murder Mystery 2 streaming March 31 on Netflix.

In it, the SNL alum and the Friends alum reprise their roles as NYC police officer Nick Spitz and his hairdresser wife Audrey Spitz.

Murder Mystery 2 – shot in France, Hawaii, and the Caribbean – also features Mark Strong, Mélanie Laurent, Jodie Turner-Smith, Enrique Arce, Tony Goldwyn, and Annie Mumolo.

It’s all part of Adam’s $275M four-movie deal his company Happy Madison Productions allegedly signed with the streaming giant in 2020.

Barrymore and Sandler famously played love interests in Frank Coraci’s 1998 rom-com The Wedding Singer, Peter Segal’s 2004 rom-com 50 First Dates, and Frank Coraci’s 2014 rom-com Blended.

Rare PDA! And the San Fernando Valley natives weren't alone as Adam's wife Jacqueline Titone, whom he kissed on the cheek onstage during the festivities

Rare PDA! And the San Fernando Valley natives weren’t alone as Adam’s wife Jacqueline Titone, whom he kissed on the cheek onstage during the festivities

Sandler and the 48-year-old Daddy Daughter Trip actress will impressively celebrate their 20th wedding anniversary on June 22

It's quite a marriage milestone in Hollywood

Marriage milestone: Sandler and the 48-year-old Daddy Daughter Trip actress will impressively celebrate their 20th wedding anniversary on June 22

Girl-dad: The Brooklyn-born comedian and Jackie are proud parents of 16-year-old daughter Sadie Madison (R) and 14-year-old daughter Sunny Madeline

Girl-dad: The Brooklyn-born comedian and Jackie are proud parents of 16-year-old daughter Sadie Madison (R) and 14-year-old daughter Sunny Madeline

Adam said of the honor earlier: 'What a nice night! I never expected anything like this. Nobody did. But it's not something we thought of in our life. But the fact that it happened and I get to say this for the rest of my life and I do have a lot of people on the street now coming up to me. They're going, "Yeah, Mark Twain, Sandman." I'm like, "Okay!" I didn't know that was going to happen so it's cool as hell'

Adam said of the honor earlier: ‘What a nice night! I never expected anything like this. Nobody did. But it’s not something we thought of in our life. But the fact that it happened and I get to say this for the rest of my life and I do have a lot of people on the street now coming up to me. They’re going, “Yeah, Mark Twain, Sandman.” I’m like, “Okay!” I didn’t know that was going to happen so it’s cool as hell’

Applause: Meanwhile, 54-year-old Jen and 48-year-old Drew - both glammed up in not-so-basic black attire - have co-starred with Adam in three films, respectively

Applause: Meanwhile, 54-year-old Jen and 48-year-old Drew – both glammed up in not-so-basic black attire – have co-starred with Adam in three films, respectively 

Streaming March 31 on Netflix! Aniston and Sandler collaborated on Dennis Dugan's 2011 rom-com Just Go with It, Kyle Newacheck's 2020 who-done-it Murder Mystery, and Jeremy Garelick's new sequel Murder Mystery 2 (pictured)

Streaming March 31 on Netflix! Aniston and Sandler collaborated on Dennis Dugan’s 2011 rom-com Just Go with It, Kyle Newacheck’s 2020 who-done-it Murder Mystery, and Jeremy Garelick’s new sequel Murder Mystery 2 (pictured)

Rich: It's all part of Adam's $275M four-movie deal his company Happy Madison Productions allegedly signed with the streaming giant in 2020

Rich: It’s all part of Adam’s $275M four-movie deal his company Happy Madison Productions allegedly signed with the streaming giant in 2020

Ready for No. 4? Barrymore and Sandler famously played love interests in Frank Coraci's 1998 rom-com The Wedding Singer, Peter Segal's 2004 rom-com 50 First Dates, and Frank Coraci's 2014 rom-com Blended (pictured)

Ready for No. 4? Barrymore and Sandler famously played love interests in Frank Coraci’s 1998 rom-com The Wedding Singer, Peter Segal’s 2004 rom-com 50 First Dates, and Frank Coraci’s 2014 rom-com Blended (pictured)

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